To do so, you can open the Run dialog box, type ‘Outlook/safe’, and then press Enter. Alternatively, you can follow the steps below to open Outlook in safe mode: Navigate to the shortcut icon of MS Outlook application. Double-click the application shortcut while holding down the CTRL key. You will see a prompt.
Note
Office 365 ProPlus is being renamed to Microsoft 365 Apps for enterprise. For more information about this change, read this blog post.
Nov 06, 2013 I am getting the following error message: Cannot start Microsoft Outlook. Cannot open the Outlook Window. The set of folders cannot be opened. The file C: Users Nancy. Jul 28, 2021 My Outlook is not working. When I try to open it says: Microsoft Outlook cannot open. The Outlook Window and the set of Folders cannot be opened. Errors have been detected in the file. Can someone acc read more. I have been told on screen that I cannot open my Outlook. I had clicked to update Apps. I cannot open it. Answered by a verified Microsoft Office Technician. Jan 13, 2021 Exit Task Manager and restart Outlook; Method 2: Open MS Outlook in Safe Mode. By opening Outlook in safe mode, you can find if the problem is caused by some faulty add-ins. If Outlook opens in safe mode without any hiccup, you must uninstall the third-party add-ins from the Outlook while running in safe mode. The steps are as follows.
Problem
When you try to run a Microsoft Office 365 ClickOnce application such as Office 365 Desktop Setup or the Office 365 Desktop Readiness Tool, you receive the following error message:
Application cannot be started. Contact the application vendor.
When you click Details, you receive a detailed error message that resembles the following:
Cause
This issue occurs if the application was cached in the ClickOnce application cache. The application must be removed from the cache before you can successfully run it.
Solution
To clear the ClickOnce application cache, follow these steps:
- Click Start, click Run, type cmd, and then click OK.
- Type the following command, and then press Enter: rundll32 dfshim CleanOnlineAppCache
To check whether the problem is fixed, follow these steps:
- If the problem is fixed, you are finished with these steps.
- If the problem is not fixed, visit https://go.microsoft.com/fwlink/?linkid=2003907 or contact support.
More information
The Application Microsoft Outlook Cannot Be Opened
For more information, see ClickOnce Unmanaged API Reference.
Can't Open Outlook On Mac
Still need help? Go to the https://go.microsoft.com/fwlink/?linkid=2003907 website.